Indications 

Tudorza Pressair is nasal medication indicated for the maintenance treatment of patients with COPD, including chronic bronchitis and emphysema. It is used to prevent bronchospasm and improve airflow in the lungs. 

Aclidinium, the active ingredient in Tudorza Pressair, is an anticholinergic medication that works by blocking the action of acetylcholine, a neurotransmitter, on the airway smooth muscles. This helps to relax and open up the airways, making it easier to breathe. 

Use and Dosage 

The recommended dose of Tudorza Pressair Inhaler is one oral inhalation of 400 mcg, twice daily. It is a breath-actuated inhaler, so you need to inhale the medication while pressing down on the green button on the top of the inhaler. 

To use Tudorza Pressair Inhaler (aclidinium bromide inhalation powder), follow these general steps: 

1. Remove the protective cap from the inhaler mouthpiece and shake the inhaler well. Check the expiration date on the inhaler and make sure it is not expired. 
2. Breathe out fully, away from the inhaler, to ensure your lungs are empty. 
3. Hold the inhaler upright with the mouthpiece facing you and place your lips tightly around the mouthpiece. Take a fast, deep breath in through your mouth, and at the same time, press down firmly on the green button on the top of the inhaler. This will release a dose of the medication. 
4. Remove the inhaler from your mouth and hold your breath for about 10 seconds, or as long as is comfortable for you. 
5. Breathe out slowly and gently away from the inhaler. 
6. If your healthcare professional has prescribed two doses per use, repeat steps 2-5 to take the second dose. 
7. If you have been instructed to rinse your mouth after using the inhaler, do so after you have completed all the necessary doses. 

Note that these steps are a general guide and the specific instructions for using Tudorza Pressair Inhaler may vary.  

Side Effects 

Common Side Effects 

• Common cold  
• Cough 
• Headache  
• Stuffy nose 
• Sore throat 
• Sinus pain 

Serious Side Effects 

• Diarrhea 
• Fall 
• Sinus inflammation 
• Stuffy nose 
• Toothache 
• Vomiting  

Cautions 

• Caution in patients with narrow-angle glaucoma: Tudorza Pressair should be used with caution in patients with narrow-angle glaucoma. This caution suggests that individuals with this condition may need to be closely monitored or may require alternative treatment options. 
• Worsening of urinary retention: There is a caution that worsening of urinary retention may occur with the use of Tudorza Pressair. This suggests that individuals with a history of urinary retention or bladder obstruction may need to exercise caution or consider alternative treatments. 
• Hypersensitivity reactions: There is a caution regarding the potential for hypersensitivity reactions, including allergic reactions, with the use of Tudorza Pressair Inhaler. Individuals who have a known hypersensitivity to Aclidinium Bromide or any of the components in the inhaler should avoid using it. 
• Cardiovascular effects: The Inhaler may cause cardiovascular effects such as an increase in heart rate or blood pressure. Individuals with certain cardiovascular conditions, such as arrhythmias or uncontrolled hypertension, may need to be cautious when using the medication. 
• Worsening of existing medical conditions: The Inhaler may worsen certain medical conditions, such as urinary retention, bladder obstruction, or prostatic hyperplasia.  
• Drug interactions: the Inhaler may interact with other medications, such as anticholinergic drugs or certain antibiotics.  
• Pregnancy and breastfeeding: The safety of the inhaler during pregnancy and breastfeeding is not well-established. Consult with your healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before using the inhaler.