Indications  

Sanctura is a prescribed medication used to treat overactive bladder (OAB), a condition characterized by uncontrollable contractions of the bladder muscles leading to frequent urination, urgent need to urinate, and lack of urinary control. 

As a muscarinic antagonist, Sanctura functions by inducing relaxation in the bladder muscles, thereby enhancing the ability to manage urination. 

Uses and Dosage 

Before starting treatment with Sanctura and with each prescription refill, carefully review its medication guide and patient information leaflet. Should any inquiries arise, do not hesitate to consult your doctor or pharmacist. 

The dosage of Sanctura may vary per individual based on age, medical condition, and response to the treatment. 

Typically, this medication is taken twice a day, as prescribed by the doctor, either on an empty stomach or 1 hour prior to meals. 

For optimal results, take Sanctura exactly as directed at around the same time(s) each day. Do not alter the prescribed dosage and frequency of intake without consulting your doctor. 

Inform your doctor if your condition does not improve or worsens. 

Side Effects 

Listed below are the potential adverse effects of Sanctura. Notify your doctor right away if any of them persists or worsens. 

Common Side Effects 

• Dry mouth or throat 
• Headache 
• Mild constipation 
• Upset stomach or gas 
• Dizziness or drowsiness 
• Dry eyes 

Serious Side Effects 

• Severe stomach pain or bloating 
• Severe constipation 
• Reduced or absent urination 
• Confusion or hallucinations 

Stop taking Sanctura and contact your doctor right away if you encounter any of the serious side effects listed above. 

Allergic Reactions 

Although rare, a severe allergic reaction to Sanctura may occur. Seek prompt medical help if you encounter any signs of an allergic response, such as: 

• Hives 
• Face, lips, tongue, or throat swelling 
• Breathing difficulties 

Not all side effects of Sanctura are included in this list. Tell your doctor if any unlisted effects occur. 

Cautions 

Before starting treatment with Sanctura, inform your doctor if you have any known allergies, particularly to trospium or other medications. 

Consult your pharmacist for additional information about Sanctura, as it may contain inactive ingredients that may cause allergic reactions or other complications. 

To ensure Sanctura is safe for you, disclose to your physician your medical background, especially if you have a history of: 

• Glaucoma 
• Kidney disease 
• Liver disease 
• Stomach/intestinal problems (e.g., blockage, constipation, ulcerative colitis) 
• Myasthenia gravis 
• Urinary retention 

Notify all your healthcare providers of any current or recently started or stopped medications, including prescription and over-the-counter drugs, vitamins, and herbal supplements, to lower the risk of drug interaction with Sanctura. 

Some of the products that may interact with Sanctura include: 

• Drugs eliminated by the kidneys (e.g., metformin, tenofovir, vancomycin) 
• Certain anti-Parkinson’s drugs (e.g., trihexyphenidyl) 
• Other antimuscarinic drugs (e.g., dicyclomine, oxybutynin, scopolamine, tolterodine) 
• Potassium tablets/capsules 
• Pramlintide 

Review the labels on all your medications, including allergy or cough-and-cold products, as they may contain ingredients that induce drowsiness. Consult your pharmacist for guidance on the safe use of such products, especially: 

• Alcohol 
• Marijuana (cannabis) 
• Specific antihistamines (e.g., cetirizine, diphenhydramine)  
• Sleep or anxiety medications (e.g., alprazolam, diazepam, zolpidem) 
• Muscle relaxants 
• Opioid pain relievers (e.g., codeine) 

The use of Sanctura may result in drowsiness, dizziness, and blurred vision. Refrain from driving or operating machinery until the effects of this medication are known. 

Sanctura may impair the body’s ability to regulate temperature in hot conditions. Ensure sufficient fluid intake throughout the duration of this treatment and avoid extreme heat exposure. Seek immediate medical attention if you experience fever or signs of heat stroke, such as dizziness, upset stomach, headache, confusion, and rapid heartbeat after exposure to heat. 

Older individuals may experience greater susceptibility to the side effects of Sanctura, such as constipation, dry mouth, drowsiness, confusion, or urinary difficulties. Drowsiness and confusion can elevate the risk of falling. 

The safety and efficacy of Sanctura in pediatric patients have not been established. 

The potential impact of Sanctura on an unborn child is uncertain. If you are pregnant or planning to become pregnant while taking this medication, inform your doctor. 

The potential transfer of trospium into breast milk and its effects on a nursing baby is currently unknown. Inform your doctor if you are breastfeeding before using Sanctura.