Indications 

Mirtazapine is prescribed for the treatment of depression, functioning to enhance mood and foster a sense of well-being. As an antidepressant, Mirtazapine operates by readjusting the equilibrium of natural neurotransmitters within the brain, thereby contributing to its therapeutic effects. 

Uses and Dosage 

Please review the Medication Guide provided by your pharmacist prior to commencing the use of mirtazapine and before each refill. Should you have any inquiries, consult your doctor or pharmacist for guidance. 

Administer this medication orally, either with or without food, following your doctor’s instructions, typically taken once daily at bedtime. The prescribed dosage is contingent upon your medical condition and response to the treatment regimen. 

Handle the tablets with clean, dry hands, and place the tablet on your tongue after opening the blister pack. The tablet dissolves rapidly and can be swallowed with saliva, eliminating the need for water or other liquids. 

Do not to break, chew, or crush the tablets. Refrain from removing any tablets from the blister pack until you are prepared to take your prescribed dose, as premature handling may impact its efficacy. 

Consistent usage of this medication is pivotal to derive its maximum benefits. To aid in remembrance, take it at the same time daily. It may take between 1 to 4 weeks to observe an amelioration in your symptoms. Avoid increasing the dose or altering the frequency of intake beyond the prescribed regimen. 

Side effects 

Allergic Reaction

Seek immediate emergency medical assistance if you exhibit signs of an allergic reaction, such as: 

• Hives 
• Joint pain 
• Fever 
• Difficulty breathing 
• Swelling in the face or throat 

Promptly notify your doctor of any new or worsening symptoms, which may encompass: 

• Changes in mood or behavior 
• Heightened anxiety 
• Occurrences of panic attacks 
• Difficulties with sleep 
• Feelings of impulsiveness 
• Irritability 
• Agitation 
• Hostility 
• Aggressiveness 
• Restlessness 
• Hyperactivity (both mentally and physically) 
• Increased depression, or any thoughts related to self-harm or suicide 

Severe Side Effects

Remeron SolTab may induce severe side effects. Contact your doctor immediately if you experience the following: 

• Racing thoughts, reduced need for sleep, engaging in unusual risk-taking behaviors, or extreme fluctuations in mood leading to heightened happiness or sadness, accompanied by unusually elevated talkativeness 
• Vision irregularities like blurred vision, tunnel vision, eye pain or swelling, or observing halos around lights 
• Sensations of dizziness leading to a potential loss of consciousness 
• Severe skin reactions such as a rash, blisters, or swelling on the palms of your hands or soles of your feet 
• Seizures 
• Low counts of white blood cells, indicated by symptoms like fever, chills, sore throat, cough, oral or nasal sores, flu-like symptoms, or difficulty breathing 
• Reduced sodium levels, characterized by symptoms like headaches, confusion, slurred speech, severe weakness, vomiting, loss of coordination, or a sense of unsteadiness 
• Immediate medical attention is necessary if you exhibit symptoms indicative of serotonin syndrome, which may include agitation, hallucinations, fever, profuse sweating, shivering, rapid heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea 

Common Side Effects

Commonly reported side effects of Remeron SolTab encompass: 

• Drowsiness and dizziness 
• Increased appetite 
• Weight gain 

Cautions 

Avoid using mirtazapine if you have recently taken a MAO inhibitor within the last 14 days, as it can lead to a hazardous drug interaction. MAO inhibitors encompass medications such as isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, among others. 

Inform your doctor about any concurrent use of stimulant medication, opioid medication, herbal products, or medications for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or for the prevention of nausea and vomiting. Interaction between these medications and mirtazapine could result in a severe condition known as serotonin syndrome. 

Adolescents and young adults may experience thoughts about suicide when initiating antidepressant treatment. Regular monitoring by your doctor and heightened awareness from family or caregivers regarding changes in mood or symptoms is crucial. 

The orally disintegrating tablet formulation may contain phenylalanine and could be harmful to individuals with phenylketonuria (PKU). 

This medication is not approved for use by individuals under the age of 18 years old.