Indications 

Protelos is a prescription medication used in the treatment of severe osteoporosis. Osteoporosis is a condition that weakens bones and makes them more prone to fractures. It can be used for postmenopausal women and adult men who have a high risk of fracture and cannot take other osteoporosis medications. 

Protelos contains strontium, which is absorbed into the bone after being released in the gut. It belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). It works by increasing bone mineral density and reducing the risk of fractures. It helps to stimulate the formation of new bone and inhibit the breakdown of existing bone. 

Use and Dosage 

Protelos is available in the form of granules, with each sachet containing 2 grams of the medication. These granules are contained within individual sachets, each carefully measured to contain 2 grams of the medication.  

This specific formulation allows for easy administration and accurate dosing, ensuring that patients receive the appropriate amount of Protelos for their treatment. By providing the medication in granule form, it offers flexibility and convenience for patients, allowing them to easily prepare the medication for oral consumption. 

To use Protelos granules, here is a general guideline based on the available information: 

1. Method of administration: Protelos granules are intended for oral use. 
2. Prepare the suspension: Empty the contents of the Protelos granules sachet into a glass. 
3. Add liquid: Add at least 30 ml (about one ounce) to the glass containing the granules. The liquid can be water or another suitable beverage. 
4. Mix well: Stir or shake the mixture thoroughly to ensure that the granules are fully dispersed and form a suspension. 
5. Drink the suspension: Once the granules are well mixed with the liquid, drink the entire suspension. 

Follow the specific instructions provided by your healthcare professional or the information leaflet accompanying the medication. They may provide additional details on the recommended dosage, frequency of administration, and any specific precautions or considerations for using Protelos granules. 

Side Effects 

Common Side Effects 

• Abdominal pain 
• Allergic reactions such as swelling, hives, or difficulty breathing. 
• Diarrhea 
• Headache 
• Joint pain 
• Muscle pain 
• Muscle spasms 
• Nausea 
• Skin rash or itching may occur in some cases. 
• Vomiting 

Serious Side Effects  

• Abdominal pain 
• Cardiovascular events, such as heart attack, stroke, and blood clots 
• Dark urine 
• Difficulty breathing 
• Dizziness 
• Fatigue 
• Itching 
• Rash 
• Stevens-johnson syndrome 
• Swelling 
• Toxic epidermal necrolysis 
• Yellowing of the skin or eyes 

Cautions 

• History of heart and circulatory problems: Protelos should be used with caution or avoided in patients with a history of heart and circulatory problems. The European Medicines Agency (EMA) recommends limiting its use to patients with no history of such issues. 
• Renal impairment: Strontium, the active ingredient in Protelos, should be used with caution in patients with renal impairment. Close monitoring may be necessary in these cases. 
• Increased risk of heart problems: There is data suggesting an increased risk of heart problems associated with Protelos. Changes in the way the medicine is used have been recommended due to this risk. 
• Liver impairment: Protelos should be used with caution in patients with liver impairment. Close monitoring of liver function may be necessary in these cases. 
• Pregnancy and breastfeeding: Protelos is not recommended for use during pregnancy or breastfeeding. The safety of Protelos in these situations has not been established, and it is important to discuss alternative options with a healthcare professional. 
• Interaction with other medications: Protelos may interact with certain medications, such as calcium supplements, vitamin D supplements, and certain antibiotics. It is important to inform your healthcare professional about all the medications you are taking to avoid potential interactions. 
• Gastrointestinal side effects: Protelos may cause gastrointestinal side effects such as nausea, diarrhea, and abdominal pain. If these side effects persist or worsen, it is important to consult with a healthcare professional. 
• Bone, joint, or muscle pain: Some patients may experience bone, joint, or muscle pain while taking Protelos. If you experience any new or worsening pain, it is important to inform your healthcare professional.