Indications 

Midamor is a prescribed medication used as an additional treatment alongside thiazide diuretics or other kaliuretic-diuretic agents for congestive heart failure or hypertension, with the following purposes: 

• Facilitating the restoration of normal serum potassium levels in patients experiencing hypokalemia due to kaliuretic diuretics. 
• Mitigating the risk of hypokalemia in vulnerable patients, such as those on digitalis therapy or with notable cardiac arrhythmias. 

Classified as a potassium-sparing diuretic, Midamor promotes the elimination of excess salt and water from the body while also limiting excessive potassium excretion by the kidneys. 

Uses and Dosage 

Before starting treatment with Midamor and with each prescription refill, carefully review its medication guide and patient information leaflet. Consult your doctor or pharmacist for guidance if you have any questions or uncertainties. 

The appropriate dosage of Midamor is based on the patient’s medical condition and response to the treatment. 

Typically, this medication is taken once a day with a meal as prescribed by the doctor. 

For optimal results, adhere to a consistent daily schedule when taking Midamor. Take it exactly as directed and refrain from altering the dosage or frequency without medical guidance. 

Continue taking Midamor even if you feel well. Consult your doctor before discontinuing this medication. 

Side Effects 

Listed below are the potential adverse effects of Midamor. Inform your doctor if any of them last or worsen. 

Common Side Effects 

• Nausea, stomach pain, gas, or loss of appetite 
• Headache 
• Rash 

Serious Side Effects 

• Increased thirst or decreased urination 
• Heavy sweating or hot and dry skin 
• Tremors, confusion, or loss of consciousness 
• Jaundice (yellowing of skin or eyes) 
• Signs of high potassium levels: 
  • Tiredness 
  • Numbness or tingling 
  • Low or unusual heart rate 
  • Muscle weakness or limp feeling 
• Signs of low levels of sodium: 
  • Headache 
  • Confusion 
  • Slurred speech 
  • Severe weakness 
  • Vomiting 
  • Loss of coordination 
  • Feeling unsteady 

Call your doctor immediately if you experience any of the severe side effects listed above. 

Allergic Reactions 

Although rare, a severe allergic reaction to Midamor may occur. Seek immediate medical assistance if you observe any of the following symptoms: 

• Hives 
• Difficult breathing 
• Swelling (especially face, lips, tongue, or throat) 

This list does not contain all the potential side effects of Midamor. If you experience any unlisted effects, tell your doctor right away.  

Cautions 

Before starting treatment with Midamor, inform your doctor and pharmacist if you have any known hypersensitivities, especially to amiloride, other medications, or any ingredients present in Midamor tablets. 

To ensure Midamor is safe for you, disclose to your physician your medical background, especially if you have a history of: 

• Untreated salt mineral imbalance (e.g., high potassium, low sodium level) 
• Kidney disease 
• Liver disease 
• Diabetes 
• Dehydration 

Inform your doctor and pharmacist about all prescription, nonprescription medications, vitamins, nutritional supplements, and herbal products you currently use or intend to use to avoid potential drug interactions with Midamor. 

Some products that may interact with Midamor include:  

• Lithium 
• Sodium phosphate products 
• Other products that can elevate potassium levels: 
  • Eplerenone 
  • Tacrolimus 
  • Cyclosporine  
  • Birth control pills containing drospirenone 
  • Potassium-sparing diuretics (e.g., spironolactone/triamterene) 
  • ACE inhibitors (e.g., benazepril/captopril) 
  • Angiotensin receptor antagonists (e.g., losartan/valsartan) 

Be sure to inform your pharmacist if you are taking cough-and-cold products, diet aids, or NSAIDs like ibuprofen and naproxen, as some of their ingredients may increase blood pressure or exacerbate heart failure. Seek guidance on their safe usage. 

Avoid potassium-containing salt substitutes and low-sodium milk products while using Midamor to prevent excessive potassium levels. 

To optimize the effectiveness of Midamor, refrain from consuming a high-sodium diet, as excess salt intake can lead to water retention. 

Inform laboratory staff and your physicians of your use of Midamor, as it may disrupt particular lab tests, such as glucose tolerance testing, leading to inaccurate results. 

Midamor can cause dizziness. Refrain from operating vehicles, using machinery, or engaging in activities requiring alertness until you can do so safely. 

Excessive sweating, vomiting, or diarrhea leading to dehydration can further decrease blood pressure and exacerbate dizziness. To prevent these effects and maintain hydration, consume adequate fluids. If you have restricted fluid intake, consult your doctor for specific guidelines. Contact your doctor if you cannot drink fluids or experience persistent diarrhea or vomiting. 

Midamor should only be used if necessary, during pregnancy. Consult with your doctor regarding the potential risks and benefits. 

The potential transfer of amiloride into breast milk and its possible effects on a nursing baby remains uncertain. Consult with your doctor before nursing an infant when taking this medication.