Indications 

Lopressor is a prescription medication indicated for treating hypertension (high blood pressure), either alone or in combination with other medicines. 

Lopressor is also indicated for long-term management of angina (chest pain), enhancement of survival post-myocardial infarction (heart attack), and the management of atrial fibrillation (a type of arrhythmia characterized by an irregular heartbeat). 

As a Beta-Blocker, Lopressor inhibits the activity of endogenous substances like epinephrine on the heart and blood vessels, thus reducing heart rate, blood pressure, and cardiac strain. 

Uses and Dosage 

Before taking Lopressor and every time you get a refill, thoroughly review its medication guide and patient information leaflet. If you have questions or concerns, do not hesitate to seek advice from your doctor or pharmacist. 

The optimal dose of Lopressor is contingent upon the patient’s medical condition and therapeutic response. Physicians usually commence treatment with a low dose, which is then gradually escalated. 

Lopressor is typically administered once or twice daily, as prescribed by the doctor, either with food or directly following a meal. 

To achieve optimal results, take Lopressor regularly at the same time each day as prescribed. Do not alter the prescribed dosage and the frequency of administration without your doctor’s approval. 

Continue taking Lopressor even if you feel well. Discontinuing the intake of this medication without medical authorization may make your condition worse. 

Side Effects 

Listed below are potential adverse reactions associated with the use of Lopressor. Inform your physician or pharmacist promptly if any of these symptoms last or worsen. 

Common Side Effects 

• Dizziness and fatigue 
• Depression, confusion, and memory impairment 
• Nightmares and sleep disturbances 
• Diarrhea 
• Mild pruritus or rash 

Serious Side Effects 

• Very slow heartbeats 
• Presyncope (light-headedness with a risk of fainting) 
• Shortness of breath (even with mild exertion) 
• Swelling 
• Rapid weight gain 
• Cold feeling in your hands and feet 

Allergic Reactions 

Severe allergic reactions to Lopressor are infrequent. However, seek medical attention immediately if you experience any symptoms listed below. 

• Rash 
• Facial, throat, or tongue swelling or itching 
• Breathing difficulties 
• Severe dizziness 

Lopressor side effects listed here are not complete. Inform your doctor promptly if you experience any unlisted side effects that cause discomfort.  

Cautions 

Before starting treatment with Lopressor, inform your doctor and pharmacist of any allergies you have, including allergies to metoprolol, other beta-blockers (e.g., atenolol, propranolol), other medications, or any ingredients in Lopressor powder. You can ask for a list of the ingredients from your pharmacist. 

Before taking Lopressor, disclose to your doctor your medical history, particularly of: 

• Certain types of heart rhythm issues (e.g., slow heartbeat, sick sinus syndrome, second- or third-degree atrioventricular block) 
• Respiratory difficulties (e.g., asthma, chronic bronchitis, emphysema) 
• Liver disease 
• Heart failure 
• Severe allergic reactions, including those requiring treatment with epinephrine 
• Blood circulation problems (e.g., Raynaud’s disease, peripheral vascular disease) 
• Mental or mood disorders (e.g., depression) 
• Certain muscle diseases (myasthenia gravis) 

Lopressor may have interactions with various drugs, including fingolimod. To avoid potential interactions, inform your healthcare provider and pharmacist of all current and planned medications, including prescriptions, over-the-counter medicines, supplements, and herbal products. 

Several medications may also interfere with the elimination of metoprolol from the body, potentially affecting its efficacy. These medications include: 

• Lumefantrine 
• Propafenone 
• Quinidine 
• SSRI antidepressants: 
  • Fluoxetine 
  • Paroxetine 
• St. John’s wort and others 

Certain products contain components that may increase your heart rate or blood pressure, or exacerbate heart failure. Inform your pharmacist if you are taking the following listed below and inquire about their safe usage. 

• Cough-and-cold products 
• Diet aids 
• NSAIDs such as ibuprofen/naproxen. 

Lopressor may cause drowsiness. Refrain from driving or operating machinery until you understand how this medication will impact you. 

The use of Lopressor during pregnancy should be limited to essential needs only, as it is unknown whether the drug may cause harm to an unborn baby. If you become pregnant or plan to while using this medication, inform your physician. 

Metoprolol is excreted in breast milk but in minimal amounts only. Consult your doctor first before nursing an infant while taking this medication.