Indications 

Invega is a prescribed drug intended for treating schizophrenia in both the acute and maintenance stages.  

Invega may also be used for the treatment of schizoaffective disorder, either as a monotherapy or as an adjunctive therapy in combination with mood stabilizers or antidepressants. 

As an atypical antipsychotic agent, Invega is believed to restore the brain’s balance of dopamine and serotonin. This action reduces hallucinations, improves the clarity of thought and positive self-perception, decreases agitation, and increases participation in daily activities. 

Uses and Dosage 

Before taking Invega, and whenever you get a refill, carefully review its medication guide and patient information leaflet. If you have any questions or clarification, consult your physician or pharmacist. 

The dosage of Invega is individualized based on the patient’s age, medical condition, and response to the treatment. It is usually taken orally once daily with sufficient water or liquid as prescribed by the doctor, irrespective of meals. 

The tablets should be ingested whole and not crushed, chewed, or split, as this can cause the drug to be released too rapidly, elevating the possibility of adverse effects. Inform your physician if you are unable to swallow tablets, as an alternative medication may be prescribed for your treatment. 

Discuss your treatment progress with your doctor and inform them if your symptoms persist. Your doctor may increase your dose gradually, but no more than once every five days if your symptoms are still distressing. 

Take Invega exactly as directed. Refrain from altering the dosage or frequency of intake without medical guidance. 

To achieve optimal results, take Invega regularly around the same time daily. Do not discontinue intake without consulting your doctor, even if you feel better. 

Side Effects 

The use of Invega may cause side effects, which are enumerated below. Should any of these persist or deteriorate, promptly notify your doctor or pharmacist. 

Common Side Effects 

• Drowsiness 
• Anxiety 
• Muscle stiffness, tremors, or shaking 
• Uncontrolled muscle movements, difficulty in walking, balance, or speech 
• Weight gain 
• Upset stomach, constipation 
• Fast heart rate 
• Stuffy nose, sore throat 

Serious Side Effects 

• Fast or pounding heartbeats, fluttering in your chest, shortness of breath, sudden dizziness, or a feeling of fainting 
• Swelling of breasts or nipples discharge, regardless of gender 
• Alterations in menstrual periods 
• Impotence, a painful or prolonged erection of the penis lasting four hours or more 
• Unexplained weight gain 
• Signs of low white blood cell count: 
  • Mouth sores 
  • Skin sores 
  • Sore throat 
  • Fever 
  • Chills 
  • Coughing 
  • Difficulty breathing
• Signs of high blood sugar levels: 
  • Increased thirst 
  • Increased urination 
  • Fruity breath odor 
  • Hunger 
• Signs of severe nervous system reaction: 
  • Rigid muscles 
  • High fever 
  • Fast or pounding heartbeats 
  • Fainting 

Promptly contact your physician if you experience any of the symptoms mentioned above. 

Allergic Reactions 

Although highly uncommon, a severe allergic reaction to Invega may occur. Seek medical attention immediately if you experience any of the following: 

• Fever 
• Swollen lymph nodes 
• Rash 
• Facial, tongue, or throat itching or swelling  
• Severe dizziness 
• Difficulty breathing 

The side effects of Invega listed here are not complete. If any unmentioned side effects arise and cause discomfort, inform your doctor immediately. 

Cautions 

Before starting treatment with Invega, inform your physician or pharmacist of any known hypersensitivities, particularly to paliperidone, risperidone (Risperdal), to any other medications, or to any of the inactive ingredients present in Invega tablet. 

To determine whether Invega is safe for you, disclose your medical history to your doctor, with a particular emphasis on the following: 

• Liver disease or kidney disease 
• Low white blood cell count or seizures  
• Parkinson’s disease or dementia 
• Dysmotility and obstruction disorders of the esophagus, stomach, or intestines, like dysphagia, peritonitis, cystic fibrosis, or Meckel’s diverticulum 
• Certain eye problems, including cataracts or glaucoma 
• Personal or family history of diabetes, high cholesterol/triglyceride levels, or heart disease 
• Breathing problems while sleeping, such as sleep apnea 

Invega may have interactions with various drugs, including metoclopramide. To avoid potential interactions, inform your healthcare provider and pharmacist of all current and planned medications, including prescriptions, over-the-counter medicines, supplements, and herbal products. 

Invega can increase heat sensitivity, leading to difficulty in cooling off and a higher risk of dehydration. Exercise or activities that generate warmth should be approached with caution. 

Invega can cause drowsiness and impair cognitive and motor function. Avoid driving or operating machinery until you are aware of the medication’s effects on you. 

Invega can also induce dizziness, lightheadedness, and fainting upon sudden transition from a supine position, particularly when beginning or escalating doses. To mitigate this, gradually rise from lying by placing your feet on the floor for a few minutes. 

Invega can temporarily affect fertility. If you intend to conceive, consult with your healthcare provider. 

The use of Invega during pregnancy should only be when necessary, as its impact on fetal development is uncertain. If you become pregnant while using Invega, notify your healthcare provider. 

Infants born to mothers treated with Invega may exhibit various symptoms, such as:   

• Tremors 
• Irritability 
• Excessive sleepiness 
• Eye twitching 
• Muscle spasms 
• Decreased appetite 
• Breathing difficulties 
• Abnormal movements 

If any of the above symptoms manifest in your infant, inform your healthcare provider immediately. 

Inform your healthcare provider if you are currently or planning to breastfeed, as paliperidone may pass into breast milk. Consult with your healthcare provider regarding the optimal method of feeding your infant while taking Invega.