Indications 

Galvus Met is a combination of vildagliptin and metformin hydrochloride which is an oral medication prescribed to improve glycemic control of people with type 2 diabetes mellitus whose blood sugar is inadequately controlled on metformin alone. It is typically used along with a balanced diet and regular exercise. Galvus Met helps to lower blood sugar levels by increasing insulin production and reducing the amount of glucose produced by the liver. 

Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which helps to control high blood sugar levels. Metformin is a biguanide that works by decreasing the amount of glucose produced by the liver and improving the body’s response to insulin. 

By controlling your blood sugar level, Galvus Met helps avoid complications of diabetes, such as heart attack, stroke, blindness, nerve problems, loss of limbs, and kidney damage.  

Use and Dosage 

Galvus Met comes in the form of oral tablet and is typically taken with meals to reduce the risk of stomach upset. It is usually taken twice daily, with one tablet in the morning and one in the evening. Take the tablet with your main meals, such as breakfast, lunch, or dinner. Take the tablet with a glass of water and swallow it whole. Do not crush, chew, or break the tablet unless specifically instructed by your healthcare provider. 

The dosage may vary depending on the severity of your condition and your response to the treatment. Take the tablet at the same time every day to maintain consistent blood sugar levels. Do not stop taking Galvus Met without consulting your doctor first.  

Take Galvus Met at the same time each day to maintain a consistent level of the medication in your body. This can help optimize its effectiveness. Regularly follow up with your healthcare provider to monitor your response to the medication and make any necessary adjustments to your treatment plan. 

Side Effects 

Common Side Effects 

• Constipation  
• Diarrhea  
• Dizziness  
• Fatigue  
• Gas  
• Headache  
• Loss of appetite  
• Nausea  
• Stomach upset  
• Weight changes 

Serious Side Effects 

• A burning sensation in the chest 
• Dark urine 
• Irregular heartbeat 
• Joint pain 
• Persistent vomiting 
• Seizure 
• Severe abdominal pain 
• Severe weakness 
• Signs of high blood sugar or hyperglycemia (increased thirst, frequent urination, increased hunger, blurred vision, fruity-smelling breath, tingling or numbness in the extremities) 
• Signs of low blood sugar or hypoglycemia (shakiness, dizziness, palpitations, confusion, irritability, difficulty concentrating) 
• Swelling of the extremities 

Cautions 

• Galvus Met should be used with caution in individuals with kidney or liver problems, as it can affect the function of these organs. Your doctor may need to adjust the dosage or monitor your kidney and liver function during treatment. 
• Galvus Met can cause low blood sugar levels, especially when taken with other diabetes medications such as sulfonylureas or insulin. Monitor your blood sugar levels regularly and be aware of the symptoms of low blood sugar, such as dizziness, confusion, sweating, and hunger. 
• There have been reports of heart failure in patients taking vildagliptin, one of the active ingredients in Galvus Met. If you have a history of heart disease or heart failure, discuss this with your doctor before starting Galvus Met. 
• Some individuals may experience allergic reactions to Galvus Met, such as rash, itching, swelling, or difficulty breathing. If you develop any signs of an allergic reaction, seek immediate medical attention. 
• Galvus Met is not recommended during pregnancy or breastfeeding. Discuss the potential risks and benefits with your doctor if you are planning to become pregnant or are currently breastfeeding. 
• Galvus Met may interact with certain medications, including other diabetes medications, blood thinners, and certain antibiotics. Inform your doctor about all the medications you are currently taking to avoid potential drug interactions. 
• There have been rare cases of pancreatitis (inflammation of the pancreas) reported with the use of vildagliptin, one of the active ingredients in Galvus Met. If you experience severe abdominal pain, nausea, or vomiting, seek medical attention immediately. 
• Metformin, one of the active ingredients in Galvus Met, can rarely cause a serious condition called lactic acidosis. This is more likely to occur in individuals with kidney or liver problems, severe infections, or dehydration. Symptoms may include muscle pain, trouble breathing, stomach discomfort, and dizziness. Seek medical help if you experience these symptoms. 
• If you are scheduled for surgery or a medical procedure, inform your healthcare provider that you are taking Galvus Met. They may advise you to temporarily stop taking the medication prior to the procedure. 
• Drinking alcohol while taking Galvus Met can increase the risk of developing lactic acidosis. Limit alcohol consumption or avoid it altogether while on this medication. 
• Some individuals may experience hypersensitivity reactions, including skin reactions such as rash, hives, or blistering. If you notice any unusual skin reactions, consult your doctor. 
• The safety and effectiveness of Galvus Met in children and adolescents under 18 years of age have not been established. Therefore, it is typically not prescribed for this age group. 
• Elderly individuals may be more susceptible to certain side effects of Galvus Met, such as low blood sugar levels. Close monitoring of blood sugar levels and careful dosage adjustments may be necessary.