Indications 

Celexa (Citalopram Hydrobromide) is an oral medication indicated for the treatment of depression. This selective serotonin reuptake inhibitor (SSRI) operates by inhibiting the neuronal reuptake of serotonin in the central nervous system (CNS), thereby resulting in an increase in serotonin levels in the brain and stimulation of nerve cells. 

Its therapeutic effect is aimed at reducing dysphoric and depressed moods, improving mood, sleep, energy levels, and overall feelings of well-being. This medication is intended to alleviate symptoms that may impact daily functioning. 

Uses and Dosage 

Read thoroughly the accompanying medication guide or informational leaflet before beginning any prescription medication regimen. If you have questions regarding the proper usage of this drug, consult with your physician or pharmacist for additional medical guidance. 

This tablet is typically administered orally, once per day, either in the morning or evening, as directed by your healthcare provider. It may be taken with or without a meal, and is recommended to swallow the tablet with a glass of water. If modification of the tablet is necessary, please seek the assistance of a pharmacist. 

Adhere to the prescribed regimen of this medication, taking it regularly and as directed by your physician. It may be helpful to establish a dosing schedule to ensure consistent administration. The frequency, dosage, and duration of treatment may vary based on factors such as age, laboratory results, medical condition, response to treatment, and concurrent medications. 

Continue taking this antidepressant, even if one feels better, to avoid potential worsening of symptoms or withdrawal. Celexa withdrawal symptoms can include headache, tiredness, mood swings, sleep changes, and brief sensations of electric shock. 

Side Effects 

Allergic Reactions

Seek emergency medical attention if experiencing signs of an allergic reaction: 

• Hives 
• Rash 
• Blisters 
• Fever 
• Joint pain 
• Difficulty breathing 
• Swelling of the face, lips, tongue, or throat 

Severe Side Effects

Report new or sudden changes in mood or behavior to a doctor immediately, including: 

• New or worse depression or anxiety 
• Panic attacks 
• Trouble sleeping 
• Impulsive, irritable, agitated, hostile, or aggressive behavior 
• Restlessness or increased activity 
• Thoughts of suicide or hurting oneself 

Contact a doctor immediately if experiencing the following symptoms: 

• Light-headedness 
• Blurred vision 
• Eye pain or redness 
• Seeing halos around lights 
• Fast or pounding heartbeats 
• Chest pain or fluttering 
• Shortness of breath 
• Sudden dizziness 
• Seizures 
• Manic episodes:
  • Racing thoughts
  • Increased energy
  • Decreased need for sleep
  • Risk-taking behavior
  • Agitation
  • Talkativeness
• Severe nervous system reaction:
  • Stiff muscles
  • High fever
  • Sweating
  • Confusion
  • Fast or uneven heartbeats
  • Tremors
• Low blood sodium:
  • Headache
  • Confusion
  • Problems with thinking or memory
  • Weakness
  • Unsteadiness

Seek medical attention for symptoms of serotonin syndrome: 

• Agitation 
• Hallucinations 
• Fever 
• Sweating 
• Shivering 
• Fast heart rate 
• Muscle stiffness 
• Twitching 
• Loss of coordination 
• Nausea 
• Vomiting 
• Diarrhea 

Common Side Effects  

• Sexual problems 
• Dizziness 
• Drowsiness 
• Dry mouth 
• Thirst 
• Increased sweating or urination 
• Loss of appetite 
• Nausea 
• Diarrhea 
• Constipation 
• Anxiety 
• Agitation 
• Shakiness 
• Weakness or fatigue 
• Sleep problems (insomnia) 
• Yawning 
• Increased muscle movement 
• Nosebleeds 
• Heavy menstrual bleeding 
• Cold symptoms (stuffy nose, sneezing, sore throat). 

Caution 

Prior to initiating therapy with citalopram hydrobromide, thoroughly disclose your medical history to your healthcare provider. This should encompass any prior history of suicide attempts, bipolar disorder, seizures, hyponatremia, liver disease, gastrointestinal disorders, bleeding issues, and glaucoma, as these conditions may impact the body’s response to this selective serotonin reuptake inhibitor (SSRI) medication.  

As citalopram is indicated for the treatment of depression, monitor for signs of suicidal ideation, including talking or thinking about death, changes in behavior, giving away personal possessions, alterations in sleep patterns, and social withdrawal. If these warning signs are observed, contact a local suicide hotline. 

Citalopram may cause QT prolongation, indicated by palpitations or an irregular heartbeat, severe dizziness, and fainting. This constitutes a medical emergency and can be prevented by staying hydrated and avoiding diuretics, as well as monitoring for low levels of potassium and magnesium, which may increase the risk of QT prolongation. 

While taking this SSRI medication, avoid alcohol consumption as it may worsen adverse effects such as dizziness, drowsiness, and blurred vision.  

Caution should be exercised when engaging in activities requiring alertness, such as driving or operating machinery.