Indications 

Doxazosin mesylate, marketed under the brand name Cardura, is an orally-administered medication that is specifically indicated for the treatment of symptoms associated with benign prostatic hyperplasia (BPH), such as frequent urination, nocturia, weak stream, and difficulty initiating urine flow.  

This medication is prescribed for hypertension management and the prevention of associated complications, such as kidney problems, stroke, and heart attack. 

Uses and Dosage 

Prior to initiating treatment with doxazosin, read the Patient Information Leaflet, if available, which can be obtained from your pharmacist. Any queries related to this medication be discussed with your physician or pharmacist. 

Doxazosin is typically administered orally, either with or without food, in accordance with your physician’s instructions, usually once daily. Doxazosin has the potential to cause a sudden drop in blood pressure, resulting in dizziness or fainting. This risk is heightened during the initial stages of treatment, following a dose increase, or after treatment is resumed subsequent to discontinuation.  

In order to avoid injury associated with dizziness or fainting, first dose of doxazosin be taken at bedtime, unless directed otherwise by your physician. Your physician will likely initiate treatment with a low dose and gradually increase it, strictly adhere to their instructions. 

The dosage of doxazosin is contingent upon your medical condition and response to treatment. Take this medication regularly and at the same time each day in order to derive the maximum benefit. In the event that you miss taking doxazosin for several days, it may be necessary to recommence treatment at a low dose and gradually increase it again. Consult with your physician for further guidance in this regard. 

Continue taking doxazosin even if you feel well, as most individuals with high blood pressure do not experience symptoms. Within one to two weeks of initiating treatment, you should notice a positive effect from the medication. Should your condition fail to improve or worsen, such as in the case of elevated or increasing blood pressure readings or a worsening of BPH symptoms, consult your physician about this. 

Side Effects 

Allergic Reactions  

Seek immediate emergency medical aid if you exhibit symptoms of an allergic reaction to Cardura, such as:  

• Breathing difficulties 
• Hives 
• Swelling of your face, lips, tongue, or throat 

Severe Side Effects

Contact your physician without delay if you experience any of the following symptoms: 

• A sensation of lightheadedness with a tendency to faint 
• Persistent abdominal pain or bloating 
• New or worsening chest pain 
• Difficulty breathing 
• Painful or prolonged erection of the penis lasting four hours or more 

Common Side Effects 

The typical side effects associated with Cardura may include: 

• Low blood pressure 
• Dizziness 
• Drowsiness 
• Headache 
• Weakness or fatigue 

Caution 

Prior to initiating treatment with Cardura, provide your medical history to your healthcare provider, including any previous eye conditions such as glaucoma or cataracts, liver or heart disease. Certain medical conditions may affect how your body responds to this alpha-blocker.  

Disclose all supplements, herbal products, prescription and non-prescription medications you are currently taking, as they may interact with this medication. 

Monitor for any allergic reactions while taking this medication. If you have a known allergy to doxazosin or any of the inactive components of the tablet, discontinue use immediately and seek emergency medical care. Symptoms of hypersensitivity include but are not limited to severe dizziness, breathing difficulties, skin rashes, swelling of the face and neck, and itchiness. 

Limit or avoid the consumption of alcohol while taking Cardura. Alcohol may intensify the side effects of doxazosin, such as dizziness and drowsiness. Caution should be exercised while driving, operating machinery, or engaging in activities that require alertness. 

Pregnant and breastfeeding mothers should use this medication only when necessary. The safety of Cardura on unborn babies and nursing infants has not been established.