Indications 

Besivance is an ophthalmic medication prescribed to treat bacterial conjunctivitis caused by susceptible isolates of bacteria. 

Belonging to the class of quinolone antibiotics, Besivance works by inhibiting the growth of bacteria, to treat only bacterial eye infections. Other types of eye infections, such as those caused by viruses, fungi, and mycobacteria, are not responsive to this medication. 

Avoid unnecessary or improper use of Besivance or any antibiotic, as this can decrease their efficacy. 

Uses and Dosage 

Before using Besivance and with each prescription refill, thoroughly review its medication guide and patient information leaflet. Seek the guidance of your physician or pharmacist for any questions or clarifications. 

During the use of Besivance or when exhibiting any signs or symptoms of an eye infection, do not wear contact lenses. Sterilize contact lenses as per the manufacturer’s instructions and consult with your doctor before resuming their use. 

The usual dosage for Besivance involves instilling one drop into the affected eye(s) three times a day, with 4 to 12-hour intervals, for 7 days. For optimal results, use this medication regularly around the same times each day to aid in remembering. 

To properly use Besivance, follow these steps: 

1. Begin by washing your hands thoroughly with soap and water. 
2. Check the dropper tip for any cracks or chips, and ensure it stays clean by not touching it or letting it touch any surfaces. 
3. Shake the bottle once by turning it upside down before each use. 
4. Tilt your head back, then use your index finger to pull down the lower lid of your eye and create a pocket. 
5. Hold the dropper as close to your eye as possible without touching it, then brace the remaining fingers against your face. 
6. Gently squeeze the dropper while looking up and allow a single drop to fall into the pocket created by the lower eyelid. Remove your finger from the lid. 
7. Keep your eye closed for 2 to 3 minutes while tipping your head down as if you were looking at the floor. Do not blink or squeeze your eyelids. 
8. Apply gentle pressure to the tear duct by placing a finger on it. 
9. Use a tissue to wipe away any excess liquid from your face. 
10. If multiple drops are required in the same eye, wait for at least 5 minutes before applying the next drop. 
11. Replace and tighten the dropper bottle cap, without wiping or rinsing the dropper tip. 
12. Finally, wash your hands again to remove any medication residue. 

Use Besivance for the entire duration prescribed, even if symptoms improve within a few days. Prematurely stopping this eye medication may permit bacteria to persist and lead to a recurrence of the infection. 

Inform your physician if your symptoms do not improve after a few days or if you experience new or deteriorating eye symptoms, such as discharge, swelling, redness, or pain. 

Side Effects 

Listed below are the side effects associated with the use of Besivance. If any of them persist or worsen, inform your doctor promptly. 

Common Side Effects 

• Eye redness 

Serious Side Effects 

• Eye drainage or crusting 
• Severe eye irritation following the use of the eye drops 
• A sensation of a foreign body or something in the eye 
• Severe eye redness or swelling 
• Fever or any indication of a new infection. 

Call your doctor right away if you have any of the serious symptoms mentioned above. 

Allergic Reactions 

In rare cases, Besivance may cause a severe allergic reaction. Seek immediate medical attention if you experience symptoms such as: 

• Rash 
• Itching or swelling (especially of the face/tongue/throat) 
• Dizziness 
• Trouble breathing 

This list does not contain all the potential side effects of Besivance. If you experience any other effects not mentioned above, promptly notify your doctor. 

Cautions 

Before using Besivance, inform your doctor and pharmacist if you have any known hypersensitivities, especially to: 

• Besifloxacin  
• Other quinolone antibiotics (e.g., ciprofloxacin, norfloxacin) 
• Other medicines 
• Any ingredients present in Besivance suspension 

Before using this ophthalmic suspension, inform your doctor or pharmacist of your medical history, particularly if you have had other eye problems. 

Besivance may interact with other eye medications. To reduce the risk of such drug interactions, inform your doctor and pharmacist about all the products and medicines you are currently taking, including prescription and over-the-counter drugs, dietary supplements, and herbal products. 

After using Besivance, you may experience temporary blurred vision. Avoid driving, operating machinery, or any activities that require clear vision until you feel confident to perform such activities safely. 

The use of Besivance during pregnancy should only be considered if deemed necessary. A thorough evaluation of the potential risks and benefits should be discussed with a healthcare professional. 

Consult your doctor before using Besivance if you are breastfeeding, as it is unclear whether besifloxacin can pass into breast milk and harm a nursing baby.