Indications  

Staxyn is a prescribed medication indicated for the treatment of erectile dysfunction (ED), a condition characterized by the inability to achieve or maintain an erection in men. 

As a phosphodiesterase (PDE) inhibitor, Staxyn functions by enhancing penile blood circulation upon sexual arousal, potentially leading to an erection. 

Uses and Dosage 

Before taking Staxyn and with every prescription refill, carefully review its medication guide and patient information leaflet. Ask your doctor or pharmacist for any questions or concerns. 

Staxyn comes as an orally disintegrating tablet and is usually taken as needed, without regard to food intake, 60 minutes before sexual activity. 

To properly take this medication. Follow these steps: 

1. Ensure your hands are dry before handling the tablet. 
2. Adhere to the instructions on the package for extracting the tablet from the blister package.  
   • Avoid attempting to force the tablet through the foil. 
3. Once the tablet is removed from the blister package, promptly place it on your tongue and close your mouth. The tablet will dissolve rapidly. 
   • Do not take this medication with any form of liquid. 

Refrain from exceeding one dose of Staxyn within a day and ensure a minimum 24-hour interval between doses. 

Inform your physician if there is no improvement in your condition. 

Side Effects 

Listed below are the potential adverse effects of Staxyn. Tell your doctor right away if any of them persist or worsen. 

Common Side Effects 

• Flushing (sudden warmth, redness, or tingling sensation) 
• Congested nose, sinus discomfort 
• Headache, dizziness 
• Stomach upset 
• Back pain 

Serious Side Effects 

• Ringing or sudden hearing loss in ears 
• Irregular heartbeat 
• Swelling in hands, ankles, or feet 
• Breathing difficulties 
• A sensation of lightheadedness or faintness 
• Seizures (convulsions) 

Stop taking Staxyn and call your doctor immediately if any of the serious side effects above are experienced. 

Cease Staxyn usage and seek urgent medical assistance if you encounter the following: 

• Symptoms of a heart attack such as: 
  • Chest pain or pressure 
  • Pain extending to the jaw or shoulder 
  • Nausea 
  • Sweating 
• Alterations in vision or abrupt loss of vision 
• A painful erection or an erection persisting over 4 hours (a prolonged erection can damage the penis) 

Allergic Reactions 

Although rare, a severe allergic reaction to Staxyn may occur. Seek prompt medical assistance in case of any signs of an allergic reaction, such as: 

• Hives 
• Facial, lip, tongue, or throat swelling 
• Labored breathing 

Not all side effects of Staxyn are included in this list. Tell your doctor if any unlisted effects are experienced. 

Cautions 

Before starting treatment with Staxyn, inform your doctor if you have any known allergies, particularly to vardenafil and other medicines. 

Consult your pharmacist for additional information regarding Staxyn, as it may contain inactive components that could lead to allergic reactions or other complications. 

To ensure Staxyn is safe for you, disclose to your physician your medical background, especially if you have a history of: 

• Heart issues like a heart attack or life-threatening irregular heartbeat in the last 6 months, chest pain (angina), or heart failure 
• Recent stroke within the past 6 months 
• Kidney disease requiring dialysis 
• Liver disease 
• High or low blood pressure 
• Dehydration 
• Penile conditions like angulation, fibrosis/scarring, or Peyronie’s disease 
• Previous instances of painful/prolonged erection (priapism) 
• Conditions elevating priapism risk, such as sickle cell anemia, leukemia, or multiple myeloma 
• Eye problems like retinitis pigmentosa, sudden diminished vision, or NAION. 
• Bleeding disorders 
• Active stomach ulcers 

Some products may interact with Staxyn, including riociguat and vericiguat. To minimize the risk of such drug interactions, inform all your healthcare providers of any current or recently started or stopped medications, including prescription/nonprescription drugs, vitamins, and herbal supplements. 

Concurrent use of Staxyn and nitrates can significantly reduce blood pressure, resulting in potential dizziness, fainting, and, in rare cases, heart attack or stroke. Avoid combining Staxyn with the following:  

• Specific medications for chest pain/angina (nitrates like nitroglycerin and isosorbide)  
• Recreational substances known as “poppers” containing amyl or butyl nitrite 

Other medications can impact Staxyn elimination, potentially influencing its effectiveness. Examples of such medicines include: 

• Azole antifungals (like itraconazole, ketoconazole) 
• Cobicistat 
• Macrolide antibiotics (such as clarithromycin, erythromycin) 
• HIV protease inhibitors (including indinavir, ritonavir) 

Avoid co-administration of Staxyn with any other product containing vardenafil or similar medications utilized for ED or pulmonary hypertension treatment, including sildenafil and tadalafil. 

Grapefruit and Seville oranges can potentially interact with Staxyn, resulting in adverse effects. Refrain from consuming grapefruit products and Seville orange marmalades. 

Staxyn orally disintegrating tablets may include phenylalanine. Consult your doctor before taking this medication if you have phenylketonuria (PKU). 

Staxyn orally disintegrating tablets are sweetened with sorbitol. Consult your doctor if you have fructose intolerance. 

Staxyn usage does not offer protection against the transmission of sexually transmitted diseases like human immunodeficiency virus (HIV). Employ “safe sex” practices like utilizing latex condoms. For further information, consult your doctor or pharmacist. 

Staxyn is not approved for female use, and its impact on pregnant or breastfeeding individuals remains uncertain.