Indications 

Revatio, which is the generic name for sildenafil, is an orally-administered medication that is specifically indicated for the treatment of pulmonary arterial hypertension (PAH), commonly referred to as high blood pressure in the lungs.  

By enhancing the ability of adults to engage in physical exercise, Revatio helps to impede the clinical deterioration associated with PAH.  

As a phosphodiesterase-5 (PDE-5) inhibitor, this medication exerts its therapeutic effects on the smooth muscle of the pulmonary vasculature, resulting in relaxation of the vascular smooth muscle cells within the lungs and consequent vasodilation effects within the systemic circulation. 

Uses and Dosage 

Prior to commencing use of sildenafil, kindly peruse the Patient Information Leaflet furnished by your pharmacist, both at the outset of treatment and with each subsequent refill. Should you have any questions or concerns regarding the medication, please consult your physician or pharmacist without hesitation. 

To address hypertension within the pulmonary arterial system, ingest this medication orally as instructed by your doctor, with or without food, typically three times daily, spaced apart by intervals of roughly four to six hours. Do not exceed the prescribed dosage nor consume this drug more frequently than prescribed. 

Consistent and regular administration of this medication is essential to maximizing its therapeutic benefit. Establishing a fixed schedule for medication intake, adhered to each day, can assist with sustaining regular use. 

Should your condition fail to improve or deteriorate over time, kindly notify your physician immediately. 

Side Effects 

Allergic Reactions

In case of an allergic reaction to Revatio, prompt emergency medical assistance is recommended. Allergic reaction symptoms may include: 

• Hives 
• Difficulty breathing 
• Swelling of the face, lips, tongue, or throat 

Severe Side Effects

Stop taking Revatio immediately and seek emergency medical attention if you experience any of the following serious side effects: 

• Chest pain or pressure, pain radiating to the jaw or shoulder, nausea, sweating (symptoms of a heart attack) 
• Changes in vision or sudden vision loss 
• Painful or prolonged erection lasting for more than 4 hours, which may damage the penis 

Please contact your doctor immediately if you encounter any of the following side effects: 

• Severe shortness of breath, cough with foamy mucus 
• Ringing in your ears or sudden hearing loss 
• Irregular heartbeat 
• Swelling in your hands, ankles, or feet 
• Convulsions or seizures 
• Feeling lightheaded or fainting 

Common Side Effects  

• Flushing (warmth, redness, or tingly feeling) 
• Headache or dizziness 
• Abnormal vision (blurred vision, changes in color vision) 
• Runny or stuffy nose, nosebleeds 
• Sleep problems (insomnia) 
• Muscle pain or back pain 
• Upset stomach 

Caution 

Disclose your complete medical history to your physician before taking this oral treatment. This includes any history of heart problems, stroke, cardiovascular diseases, penis conditions like priapism, eye problems, ear problems, or lung conditions. 

Some disorders or diseases may significantly affect your response to treatment. You must inform your physician of all prescription and nonprescription drugs you are taking as they may interact with sildenafil. 

While taking this medication, be alert to signs of an allergic reaction. Do not take this oral medication if you have a known allergy to sildenafil or any of its inactive ingredients. Symptoms of severe hypersensitivity include difficulty breathing, severe dizziness, swelling of the face and neck, skin rashes, and hives.  

Although rare, sudden decreased vision or NAION is a possible adverse reaction to Revatio. People over the age of 50 and those with hypertension, diabetes, high cholesterol, or heart disease are more susceptible to this condition. If you are suffering from any of these conditions, inform your physician before taking this medication. 

This drug may cause dizziness and lightheadedness. Take extreme caution when performing activities that require alertness, such as using machinery or driving. Furthermore, limit alcohol intake, as it may aggravate side effects. 

If you are pregnant or breastfeeding, consult your physician before taking this medication, as it may pose a risk of harm to your unborn baby or breastfed child. Always remember that the potential benefits should outweigh the potential risks.