Indications 

Orudis EC is used for the management of pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, and primary dysmenorrhea (menstrual pain). It is also indicated for the treatment of primary dysmenorrhea (menstrual pain). 

Orudis EC contains ketoprofen, which belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing pain, inflammation, and fever by inhibiting the production of certain chemicals in the body. 

It is in an enteric-coated formulation. Enteric coating is a special coating applied to oral medications that allows them to pass through the stomach unchanged and dissolve in the intestines instead.  

Use and Dosage 

Ketoprofen EC delayed release tablets should be taken by mouth on an empty stomach, at least 1 hour before meals or 2 hours after meals as directed by your doctor, usually 1 to 4 times daily or as needed. Take it with a full glass of water unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking the tablet. 

Swallow this enteric-coated tablet whole. Do not crush or chew enteric-coated tablets. Doing so can increase stomach upset and increase the risk of side effects. Again, to reduce your risk of stomach bleeding and other side effects, take the tablet at the lowest effective dose for the shortest possible time. Do not increase your dose or use it more often or for longer than prescribed, as it can increase the risk of side effects. 

If you miss a dose of ketoprofen EC delayed release tablets, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. 

Side Effects 

Common Side Effects 

• Bloating  
• Blurred vision 
• Constipation  
• Diarrhea  
• Dizziness  
• Drowsiness  
• Dry mouth  
• Gas  
• Headache  
• Heartburn  
• Increased sweating  
• Lightheadedness  
• Loss of appetite  
• Nervousness  
• Ringing in your ears.  
• Runny nose  
• Skin itching or rash  
• Stomach pain  
• Unusual tiredness  
• Upset stomach  

Serious Side Effects 

• Allergic reaction (hives difficulty breathing or swelling of your face lips tongue or throat)  
• Bloody or tarry stools  
• Chest pain  
• Confusion  
• Depression  
• Fast or irregular heartbeat 
• Fever  
• Urinating less than usual or not at all  

Cautions 

• Kidney problems: NSAID medications, including ketoprofen, can sometimes cause kidney problems. Monitor kidney function and inform your healthcare provider if you have any pre-existing kidney conditions. 
• Gastrointestinal effects: Ketoprofen can increase the risk of stomach ulcers, bleeding, and other gastrointestinal issues. Individuals with a history of gastrointestinal problems should exercise caution when using Orudis EC. 
• Cardiovascular risks: NSAIDs, including ketoprofen, may increase the risk of heart attack, stroke, and other cardiovascular events. This risk may be higher in individuals with pre-existing heart conditions or those taking high doses for long periods. 
• Allergic reactions: Some individuals may be allergic to ketoprofen. Seek medical attention if you experience symptoms such as rash, itching, swelling, or difficulty breathing. 
• Interactions with other medications: Ketoprofen can interact with other medications, including blood thinners, diuretics, and certain antidepressants. Inform your healthcare provider about all the medications you are taking to avoid potential interactions. 
• Pregnancy and breastfeeding: Ketoprofen should be used with caution during pregnancy and breastfeeding, and the potential risks and benefits should be discussed with a healthcare provider.