Indications 

Coreg is a prescription drug that is commonly administered along with other medications to alleviate the symptoms of the following conditions: 

• Mild to severe chronic heart failure 
• Left ventricular dysfunction in clinically stable patients following myocardial infarction 
• Hypertension 

Categorized as an alpha/beta-adrenergic blocking agent, Coreg works by inhibiting the receptors of the adrenergic nervous system.  

This action leads to a decrease in both heart rate and the strength of contractions, reducing the workload on the heart. It can also impede the activation of receptors in the arteries, inducing relaxation and decreasing blood pressure. 

Uses and Dosage 

Before starting treatment with Coreg and with each subsequent refill, thoroughly review its patient information leaflet and medication guide. For any inquiries or clarification, seek advice from a qualified healthcare professional. 

Use Coreg exactly as prescribed by your doctor. Do not lessen or exceed the recommended dosage or take the medication for a duration shorter or longer than prescribed. 

Coreg’s dosage and length of intake are individualized based on the medical condition and response to the treatment. It is usually given at the lowest dose and is gradually titrated upwards to allow the body to adjust to the medication. 

Typically, Coreg is ingested twice a day in conjunction with a meal. For optimal efficacy, it should be consumed at the same time of the day daily. 

Do not stop taking this medication without your doctor’s approval; abruptly stopping may cause chest pain or a heart attack. 

The optimal effect of this medication in treating hypertension may take approximately 1 to 2 weeks to manifest. Despite feeling well, continue to take this medication, for hypertension often does not have noticeable symptoms. 

Side Effects 

Potential adverse reactions associated with the use of Coreg are listed below; if you experience persistent or worsening symptoms, inform your physician or pharmacist 

Common Side Effects 

• Dizziness 
• Slow heartbeats 
• Diarrhea 
• Weight gain 
• Dry eyes 
• Problems wearing contact lenses 

Serious Side Effects  

• Lightheadedness 
• Irregular or slow heartbeats 
• A sensation of cold or numbness in the digits 
• Chest pain 
• Dry cough 
• Wheezing 
• Chest tightness 
• Edema 
• Rapid weight gain 
• Dyspnea 
• Increased thirst 
• Increased urination 
• Dry mouth 
• Fruity breath odor 

Get medical help immediately if any of the above serious side effects occur. 

Allergic Reactions 

Severe allergic response to Coreg is rare; however, seek medical attention immediately if any of the following symptoms occur: 

• Hives 
• Severe dizziness 
• Respiratory distress 
• Facial, lip, tongue, or throat swelling 

This is an incomplete list of potential adverse reactions associated with Coreg. If any unlisted side effects prove to be bothersome, consult with a healthcare professional. 

Cautions 

Before starting treatment with Coreg, inform your physician or pharmacist of any hypersensitivity to the medication or any other allergies.  

This medication may contain inactive ingredients that may elicit allergic reactions or other complications. For further information, consult with your pharmacist. 

Disclose your medical history to your doctor, specifically of: 

• Certain types of heartbeat/heart rhythm issues, including:
  • Slow/irregular heartbeat
  • Sick sinus syndrome
  • Second- or third-degree atrioventricular block 
• Breathing problems like asthma, chronic bronchitis, or emphysema 
• Severe heart failure necessitating hospitalization 
• Liver disease, kidney disease 
• Blood circulation disorders, such as Raynaud’s disease, peripheral vascular disease 
• Severe allergic reactions, including those requiring treatment with epinephrine 
• Overactive thyroid disease (hyperthyroidism) 
• A specific type of tumor (pheochromocytoma) 
• Vasospastic angina or variant angina 
• A certain muscle disease (myasthenia gravis) 
• Certain eye problems, including cataracts, or glaucoma 

To avoid drug interactions, tell your doctor and pharmacist all prescription/nonprescription medications, supplements, and herbal products you are presently taking or intend to take.  

Be sure to mention if you are taking the following medications below, as they may contain ingredients that can exacerbate heart failure or increase heart rate and blood pressure. 

• Cough and cold medicines 
• Dietary supplements 
• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen 

Coreg may cause drowsiness, dizziness, or lightheadedness, particularly when initiating therapy or when the dosage is escalated. Caution should be exercised during the first hour following medication administration. Refrain from driving or operating machinery until you are aware of the medication’s impact on you. 

Insufficient and inconclusive research has been conducted on pregnant women to establish safety and efficacy. Utilization of Coreg during pregnancy is only recommended when the potential advantages exceed the potential hazards to the developing fetus. 

The transfer of carvedilol into breast milk is uncertain, but it is unlikely to occur in large quantities. However, there is a low risk of adverse effects on the nursing infant. Before breastfeeding, consult a healthcare provider.