Indications 

Airduo Respiclick is a fixed-dose combination inhaler containing fluticasone and salmeterol indicated for treating asthma in patients 12 years old and above. 

Fluticasone is a corticosteroid that reduces airway irritation and inflammation, while salmeterol is a long-acting beta-agonist (LABA) that relaxes the airway muscles, allowing for easier breathing. 

Airduo Respiclick is intended for patients whose asthma is not adequately managed by a long-term control medication, such as an inhaled corticosteroid, or those who require combination treatment with an inhaled corticosteroid and LABA. 

Airduo Respiclick is not intended as a rescue medication and is ineffective for the prompt treatment of asthma or bronchospasm attacks. In such cases, adhere to the prescribed regimen for quick-relief inhalers, such as albuterol.  

Uses and Dosage 

Before using Airduo Respiclick and with each prescription refill, carefully read its medication guide and patient information leaflet. In case of any inquiries, consult your physician or pharmacist. 

The dosing of Airduo Respiclick is determined by individual medical conditions and treatment response. Typically, it is used twice daily, 12 hours apart in the morning and evening. 

To use the inhaler, follow these steps: 

1. Open 
   1. Hold the inhaler upright and fully open the yellow cap until it “clicks.” 
   2. Each “click” indicates that one dose is ready for inhalation. 
   3. To ensure proper usage, maintain an upright position while opening the yellow cap. 
   4. Do not hold or manipulate the inhaler in any other manner while opening the yellow cap. 
   5. Avoid opening the yellow cap until you are prepared to administer a dose. 
2. Inhale 
   1. Exhale completely through your mouth before inhalation. 
   2. Avoid exhaling into the mouthpiece of the inhaler. 
   3. Place the inhaler’s mouthpiece in your mouth and seal your lips around it tightly. 
   4. Avoid obstructing the vent above the mouthpiece with your fingers or lips. 
   5. Inhale deeply and rapidly through your mouth to deliver the medication to your lungs. 
   6. Take the inhaler out of your mouth. 
   7. Hold your breath for approximately 10 seconds, or as long as it is comfortable. 
   8. Airduo Respiclick delivers a fine powder medication that may or may not be noticeable in taste or sensation. Do not administer an extra dosage, regardless of whether you feel or taste the medicine. 
3. Close 
   1. Close the yellow cap securely over the mouthpiece. 
   2. Ensure that you close the yellow cap after each inhalation to prepare for the next dose. 
   3. Rinse your mouth with water after each inhalation without swallowing. 

When using other inhalers concurrently, allow at least one minute between each medication’s usage and use Airduo Respiclick as the last inhaler. 

Use Airduo Respiclick regularly around the same time daily, exactly as prescribed, for optimal results. Refrain from altering the dose and frequency of use or discontinuing its use without consulting your doctor. 

Side Effects 

Listed below are the side effects associated with the use of Airduo Respiclick. If any of these symptoms persist or worsen, inform your doctor promptly. 

Common Side Effects 

• Headache 
• Muscle, bone, or back pain 
• Nausea 
• Vomiting 
• Thrush 
• Throat irritation 
• ongoing cough 
• Hoarseness or deepened voice 
• Cold symptoms: 
  • Stuffy nose 
  • Sneezing 
  • Sore throat 
• Signs of an ear infection (in a child): 
  • Fever 
  • Ear pain or full feeling 
  • Trouble hearing 
  • Drainage from the ear 
  • Fussiness 

Serious Side Effects 

• Wheezing, choking, or other breathing problems after using Airduo Respiclick 
• Fever 
• Chills 
• Cough with mucus 
• Feeling short of breath 
• Chest pain 
• Fast or irregular heartbeats 
• Severe headache 
• Pounding in the neck or ears 
• Tremors 
• Nervousness 
• Blurred vision, tunnel vision, eye pain, or seeing halos around lights 
• Signs of thrush (a fungal infection): 
  • Sores or white patches in the mouth or throat 
  • Trouble swallowing 
• Indications of high blood sugar: 
  • Increased thirst 
  • Increased urination 
  • Dry mouth 
  • Fruity breath odor 
• Indication of low potassium level: 
  • Leg cramps 
  • Constipation 
  • Irregular heartbeats 
  • Fluttering in the chest 
  • Increased thirst or urination 
  • Numbness or tingling 
  • Muscle weakness or limp feeling 
• Signs of a hormonal disorder: 
  • Worsening tiredness or weakness 
  • Feeling light-headed 
  • Nausea 
  • Vomiting 

Call your doctor immediately if any of the serious side effects above occur. 

Allergic Reactions 

Airduo Respiclick rarely causes severe allergic reactions. However, seek emergency medical help if you experience the following signs of an allergic reaction: 

• Rash 
• Itching or swelling, especially of the throat, tongue, and face 
• Severe dizziness 
• Trouble breathing 

This list does not contain all the potential side effects of Airduo Respiclick. Notify your doctor promptly if you experience any unlisted effects. 

Cautions 

Before using Airduo Respiclick, tell your doctor or pharmacist if you have any known allergies, especially to: 

• Fluticasone  
• Salmeterol 
• Milk proteins 
• Any medications 
• Any ingredients present in the Airduo Respiclick inhaler 

To ensure Airduo Respiclick is safe for you, disclose to your physician your medical background, specifically regarding any history of: 

• Past/present infections (e.g., tuberculosis or herpes) 
• Hypertension (high blood pressure) 
• Osteoporosis (bone loss) 
• Heart disease (e.g., chest pain, heart attack, or irregular heartbeat) 
• Hyperthyroidism (overactive thyroid) 
• Diabetes 
• Eye problems (e.g., cataracts or glaucoma) 
• Seizures 
• Liver disease 

Various medications may interact with Airduo Respiclick, including aldesleukin. To reduce the risk of drug interactions, apprise your healthcare provider about all the medicines you are presently taking, including prescription and non-prescription medications, as well as dietary supplements and herbal products. 

Certain medications can impact the elimination of fluticasone and salmeterol from the body, which may affect their efficacy. Such medications include: 

• Azole antifungals (e.g., ketoconazole) 
• Cobicistat 
• Macrolide antibiotics (e.g., clarithromycin) 
• HIV protease inhibitors (e.g., lopinavir) 
• Nefazodone 
• Ritonavir 
• Telithromycin 
• Others 

Inform your doctor about the usage of other LABA medications, like formoterol (Perforomist, in Dulera, in Symbicort) or salmeterol (Serevent, in Advair), as they should not be used in conjunction with Airduo Respiclick. Your doctor will provide guidance on which medication to use and discontinue. 

Airduo Respiclick may increase the risk of infections, mask their symptoms, and worsen existing ones. To minimize the risk, avoid close contact with people with contagious infections like chickenpox, measles, and flu. Contact your doctor for further information or if you have been exposed to an infection. 

Airduo Respiclick can temporarily impede a child’s growth if used for an extended period, but uncontrolled asthma can also affect growth. Having regular check-ups with a doctor to monitor your child’s height is recommended. 

Extended use of Airduo Respiclick in adults can elevate the likelihood of bone loss (osteoporosis). Consult with your doctor regarding the associated risks and potential treatments. 

Airduo Respiclick usage during pregnancy is only recommended when essential. Consult with your doctor to weigh the potential risks and benefits before use. 

It is unclear whether fluticasone or salmeterol affects breast milk or breastfed infants. Consult your doctor before breastfeeding for further guidance.